Opioid Analgesic REMS: To make certain the many benefits of opioid analgesics outweigh the pitfalls of addiction, abuse, and misuse, a REMS is necessary for these products. Less than the necessities with the REMS, drug firms with accredited opioid analgesic products should make REMS-compliant education schemes available to healthcare providers. https://recreational-pills.com/product/wockhardt-promethazine-with-codeine/