G allele (A118G) are poor responders to morphine, and need increased doses on the drug to relieve pain. On top of that, morphine and its metabolites really have to cross the BBB and penetrate the CNS to perform their action: it was demonstrated that pain relief variability, in most https://deanuofwm.blogofchange.com/29052824/the-smart-trick-of-proleviate-natures-morphine-that-nobody-is-discussing