The reverse transcriptase also has ribonuclease action that degrades the viral RNA over the synthesis of cDNA, and DNA-dependent DNA polymerase exercise that generates a sense DNA from your antisense cDNA.[sixty nine] Collectively, the cDNA and its complement type a double-stranded viral DNA that's then transported into the mobile nucleus. https://hivhub.in/hiv-epidemic-in-india-trends-and-state-wise-distribution/