There exists a launch of norepinephrine in the descending inhibitory bulbospinal neurons that binds to alpha-2-receptors within the dorsal horn to decrease afferent suffering transmission and produce analgesia. Hence, medications like clonidine that target alpha-two receptors can impact the transmission of pain. Applies to clonidine: oral tablet, oral tablet https://bookmarknap.com/story10184838/indicators-on-onolidine-you-should-know