There exists a launch of norepinephrine from the descending inhibitory bulbospinal neurons that binds to alpha-2-receptors from the dorsal horn to lessen afferent agony transmission and deliver analgesia. Therefore, medication like clonidine that target alpha-two receptors can impact the transmission of pain. This data isn't a substitute for healthcare https://getsocialsource.com/story5203754/onolidine-fundamentals-explained