Even though fewer typical, one of the most significant Negative effects of ursodiol are explained down below, together with what to do when they come about. Nonabsorbed ursodiol passes into your colon in which it is mostly 7-dehydroxylated to lithocholic acid. Some ursodiol is epimerized to chenodiol (CDCA) by https://www.youtube.com/watch?v=A07qHOeWON8